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Jury selection begins Monday in the federal trial of Joaquin "El Chapo" Guzman.

Guzman was captured in Mexico in 2016 and extradited to the United States to stand trial.

U.S. district court judge Brian Cogan will preside over the process behind closed doors.

A look at those concerns for a trial that is starting Monday with jury selection.

Judge Cogan also raised concerns at the hearing about the prosecutors' planned case at the hearing. If convicted, he faces life in prison.

The now imprisoned brothers paid a steep price for flipping: Prosecutors say in 2009 their father was murdered in Mexico by a cartel hit team.

They will also be escorted in and out of the court by guards.

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American prosecutors have accused Joaquin Guzman of overseeing a multibillion-dollar drug operation and a ruthless campaign of murders and kidnappings of his rivals. The 12 jurors, with six alternates, will remain anonymous.

It is alleged that he spent a quarter of a century smuggling more than 155 tonnes of cocaine into the United States.

"'El Chapo Guzman is the world's #1 drug criminal", DEA spokesperson Rusty Payne told Forbes after his apprehension in 2014.

According to the indictment, the Sinaloa cartel, which Guzman is accused of leading from 1989 to 2014, became "the largest drug trafficking organisation in the world. with thousands of members".

U.S. prosecutors contend from 1989 to 2014, the Sinaloa cartel smuggled at least 155 tonnes of cocaine into the United States, as well as heroin, methamphetamine and marijuana, raking in US$14 billion (S$19 billion).

In his way now is a lineup of government witnesses who survived the wave of violence and are expected to give details about the ruthless way he kept power for 20 years in the cutthroat world of worldwide drug trafficking. Some have even been hiding in special jail units and others in witness protection programs, WNBC-TV reported. Instead, she has attended nearly all his pretrial hearings, waving and blowing him kisses from the gallery. Mexican authorities then recaptured the fugitive in January 2016.

El Chapo notoriously escaped from confinement in Mexico twice, which is in part the reason for the extreme security measures surrounding his confinement and extra measures during any of his transportation. He was rearrested in 2014 only to escape 14 months later from a tunnel dug into the prison.