President Trump responded to the article, declaring it "really a disgrace".
The unsigned piece appeared to reinforce the claims made in the new book by investigative journalist Bob Woodward, which describes a virtual cabal of like-minded White House and cabinet officials scheming to prevent Trump from taking decisions damaging to the USA economy and national security.
An anonymous senior Trump official published a blistering op-ed Wednesday in the New York Times denouncing the president and describing a "resistance" within his own administration working against him.
"We want the administration to succeed and think that many of its policies have already made America safer and more prosperous".
The White House has called for the resignation of the senior administration official who wrote the piece. Woodward said, "I stand by my reporting".
The unidentified senior aide claims members of the administration had explored the possibility of removing Trump from office using the 25th amendment, a constitutional mechanism to allow for the replacement of a sitting president who is "unable to discharge the powers and duties of his office", but had decided against it. In a meeting about the Korean Peninsula, Trump's comments left Secretary of Defense Jim Mattis to say that Trump understood the matter at hand like a "fifth or sixth grader".
In the highly unusual op-ed, the author writes that "President Trump is facing a test to his presidency unlike any faced by a modern American leader".
Washington has been gripped by speculation over the author of the column, which painted a damning portrait of the president's "amorality" and his "impetuous, adversarial, petty and ineffective" leadership approach.
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When asked about the allegations, US Ambassador to the UN Nikki Haley denied ever hearing threats made by Trump against al-Assad. What are we dealing with this idiot for?'" The US remains part of both trade agreements as it negotiates new terms.
Ivanka and her husband, senior adviser Jared Kushner, have been controversial members of the administration, reportedly contributing to tensions with other administration members who see their senior positions and unfettered access to the president as exclusively due to nepotism.
Mr Mattis acknowledged Mr Trump's request then, after the conversation, told an aide he wouldn't do "any of that".
"It may be cold comfort in this chaotic era, but Americans should know that there are adults in the room", the author continued. We fully recognize what is happening.
Sanders railed against the writer of the piece, saying that they have "chosen to deceive, rather than support, the duly elected President of the United States". Trump, the writer argues, holds none of the ideals held dear by conservatives and the Republican Party, adding that the president's impulses tend to be anti-trade and anti-democratic.
White House spokeswoman Sarah Huckabee Sanders branded the piece "pathetic, reckless, and selfish" and condemned the Times for publishing it.
"There is a quiet resistance within the administration of people choosing to put country first". "This coward should do the right thing and resign".
The Times notes that it took an unusual step by publishing an anonymous op-ed.
The essay immediately triggered a wild guessing game as to the author's identity on social media, in newsrooms and inside the West Wing, where officials were blindsided by its publication.