More than 3.2 million people were registered to vote in the referendum, with more than 100,000 new voters registering ahead of the poll.
However, in 2010, the European Court of Human Rights ruled that Ireland was violating the European Convention of Human Rights because the rules surrounding what is and isn't a legal abortion were blurred.
The weather is not expected to impact on the turnout. And Catholics are the most likely to be undecided - 15 percent answering don't know or preferring not to say, against 5 percent of those with no religion.
"If the referendum doesn't pass these women will continue to have to travel overseas in their thousands", Varadkar added.
"It is an opportunity to face reality and to support women here in our own country".
"More and more people are realising that this government has planned to introduce an extreme abortion law, the only way to stop this is to vote "No", said Mary Butler, an anti-abortion lawmaker from the main opposition party, Fianna Fail.
A campaign emerged and "pro-life" anti-abortion rights groups lobbied for constitutional protection of the "unborn".
Mr McGuirk said the key to a No victory will be older voters. Akkamahadevi says that though she was in the hospital, she had checked with her brother to find out if her parents had reached home safely.
Campaigners on both sides of the referendum have set up crowd funding initiatives to help fly back to Ireland those who want to vote but could not afford it.
Currently, the 8th amendment, a clause in the Irish constitution, gives equal right to life of the mother and the unborn.
Mr Harris has promised that abortions will only be granted after the first trimester if there is a risk to the life, or of serious harm to the health of, a pregnant woman.
Abortion will remain illegal in the country in nearly all circumstances until Ireland's legislative body, the Oireachtas, passes a law legalizing the practice nationwide.
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Thousands of people living overseas returned home to vote.
Exit polls also indicated that women voted for the repeal of the 8th of Amendment by 72% where as men supported the repeal at 65%.
Gardai were last night escorting boxes to local court offices in each constituency.
Canvassers were out on the streets holding up signs and wearing t-shirts, mindful of the law requiring them to stay at least 50 metres from a polling station.
We have the journalist documenting every wonderful airport entry. "We are very positive about the outcome", he said.
"Opinion polls have been wrong before".
She said her vote would be one for solidarity and compassion, "a vote to say, I don't send you away any more".
There have been six referendums on the matter of abortion in the past 35 years in Ireland, and the issue has long divided the country.
"I think there are a lot of people who are reluctant to speak their minds".
The voting took place on a day that was sunny throughout much of Ireland, which may have bolstered turnout.
Johannes Gaultier, 28, travelled from Germany via the United Kingdom to go back and vote no in the referendum. "We came back to Bengaluru on October 24 and on 28, we were informed that she is no more". "Of course I was coming home". Those who don't have the means to travel sometimes find other ways to have abortions, albeit unsafely and illegally.
And Ireland's abortion referendum has reached further fields than our islands, with A-list celebrities weighing in on the divisive debate.