The loss left the champions in third place on 51 points, a whopping 14 points adrift of leaders Barcelona and seven behind city rivals Atletico in second, with both teams having a game in hand. Atletico hosts Leganes on Wednesday and Barcelona visits Las Palmas on Thursday.
They scored a goal in the last minute, but there's no need for us to go over it again. Despite the goal scoring opportunities, Madrid missed a bit everything and played a terrible second half.
No sooner had Madrid impressed on Saturday against Alaves by winning five fixtures in a row for the first time in 2017-18 than suffered another setback and it is really the story of their season.
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Their previous league win came eight rounds ago, at Levante UD. But Zidane's XI still should have had enough quality to beat an Espanyol side with a terrible record against Madrid in recent seasons.
At least Barca fans can't complain that Espanyol have let Madrid have an easy three points after they inflicted a fifth league defeat of the season on Zidane's side - more than they lost in all competitions in the whole of last season.
Espanyol probably edged the game and Moreno had a first-half goal ruled out for a marginal offside call. It's a defeat that hurts and it's a poor result. We always look for the win and ultimately we were unable to.
Portu scored a 14th-minute victor to put Girona in seventh place, two points behind sixth-place Sevilla.