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It is not yet known how the popular herbal supplement could have been contaminated with salmonella, nor has the outbreak investigation identified a common brand or supplier of kratom. And on Tuesday the botanical was linked to 28 cases of salmonella poisoning, including eight that had been confirmed to have used kratom.

The CDC report is the latest in a string of advisories about kratom issued by federal agencies including the Food and Drug Administration, which likened the substance to an addictive opioid, and the Drug Enforcement Agency, which moved to criminalize it.

A total of 28 people from 20 states have been infected with the outbreak strain of Salmonella I 4, [5], 12:b:-; 11 hospitalizations have been reported. This outbreak associated with kratom-containing capsules, teas and powders, underscores the risk that harmful bacteria may contaminate these products when not subjected to manufacturing controls to eliminate that risk, in addition to the overall safety concerns for kratom itself. The substance is often consumed in the form of powdered raw leaves, though sometimes it is made into a tea or other drink.

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Notwithstanding lightening torment, kratom is expended for its stimulant impacts and used to treat heroin or morphine reliance, as it is said to lessen withdrawal desires. The agency also began taking action to prevent dietary supplements containing kratom from entering the US. According to an FDA analysis, also released on February 6, one of the main compounds in kratom-mitragynine-may bind to the same kinds of receptors in the body as an opioid.

The Drug Enforcement Administration is looking at a strong restriction on the sales of kratom, which is now traded freely on the internet and in some stores. There are now no FDA-approved therapeutic uses of kratom and importantly, the FDA has evidence to show that there are significant safety issues associated with its use. No deaths have been reported thus far.

"I want to be clear on one fact: there are now no FDA-approved therapeutic uses of kratom", Gottlieb said.