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The movement was formed after a deluge of allegations disrupted or ended the careers of powerful male leaders in entertainment and also in big business, politics and the media, sparked by the Harvey Weinstein Scandal. Signatories include actresses America Ferrera, Rashida Jones, Ashley Judd, Eva Longoria, Natalie Portman, Kerry Washington, and Reese Witherspoon, as well as showrunners Shonda Rhimes and Jill Soloway.

Since October, when dozens of women began coming forward to accuse producer Harvey Weinstein of sexual misconduct, numerous men in prominent industries have been forced to resign over sexual harassment claims, including top editors at NPR.

The initiative, which is called "Time's Op" was announced on Monday in a full-page advert in the "New York Times".

"We're finally hearing each other, and seeing each other, and now locking arms in solidarity with each other, and in solidarity for every woman who doesn't feel seen, to be finally heard", she said, according to the Times.

The Time's Up project is described as a "unified call for change from women in entertainment for women everywhere".

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The Time's Up website details and defines what sexual harassment is, and what to do if it happens to you.

Time's Up will include a legal defence fund for victims across different industries, reportedly backed by $US13 million ($16.7 million) in donations, and will advocate for legislation combatting workplace harassment.

The initiative also requested women actors to wear black at the red carpet of the upcoming Golden Globes Awards.

Producer Harvey Weinstein became synonymous with sexual harassment after the New York Times exposed his history of predatory behaviour against women in October previous year.