He was also involved in an unbeaten 104-run stand with Ross Taylor.
The Black Caps have extended their winning streak to nine games across all formats after Martin Guptill and Ross Taylor guided them past a revised total of 151, in a rain-disrupted second one-day global against Pakistan.
Ferguson was the pick of the bowlers with three wickets, while Southee and Astle snapped up two wickets apiece.
When play resumed under the Duckworth-Lewis system New Zealand's target was revised to 151 in 25 overs meaning they had 11 overs left to make 87. The opener continued his six-hitting spree to knock off the remaining runs nearly singlehandedly while hapless Pakistan fielders could only watch the ball run to the fence, or sail over it.
Martin Guptill and Colin Munro established an 83-run opening partnership for New Zealand before Hasan Ali picked Munro's wicket.
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The Pakistan cricket team, beaten in the series opener which was also impacted by rain, had earlier elected to bat and reached 246-9 thanks to some lower-order hitting.
In a repeat of the first worldwide, which New Zealand won by 61 runs under the Duckworth-Lewis system, Pakistan were always under pressure after losing early wickets and fell short of a par score at Saxton Oval where teams which bat first in ODIs average 260. By losing nine wickets in fifty overs Pakistan scored 246 runs.
On Tuesday Sarfraz took the opposite tack and chose to bat first but the result was the same.
Pakistan, missing form opener Fakhar Zaman who was rested with a bruised right thigh, felt the pressure. The best was his 45-run stand with Shoaib Malik (27) for the fourth wicket and when he was out for 60 Pakistan were in trouble at 127-6. Rumman Raees, Mohammad Amir, Hasan Ali and Ashraf all conceded 57 or more runs each - all struggling in the extremely windy conditions - allowing the home team to pile on a 315-run total. An over after successfully reviewing a caught-behind call, he became the first of many to gift-wrap his wicket - pulling a short ball well outside of off-stump off Trent Boult straight down the throat of Munro at square leg.
Lockie Ferguson finished with 3 wickets for 39 runs from his 10 overs, while Todd Astle and Tim Southee took 2 wickets each.